Department of Cancer Research
Our vision is to impact on patients’ life by advancing the fight against cancer. Based on strong scientific track-records, we focus on priority research areas and provide research expertise covering the most common and/or malignant cancer types representing a health burden in Luxembourg. The department also represents a state-of-the-art training ground for next generation cancer researchers and acts as a reference point for cancer research in Luxembourg.
Mission
The main mission of the Department of Cancer Research is to advance the treatment options of cancer and reduce the cancer burden within the Luxembourg population and beyond. We do so through research excellence in priority areas covering the basic, translational and clinical research landscape to foster personalised medicine programs. Our activities focus on difficult to treat cancers and our teams have dedicated expertise in cancer immunology, the tumour microenvironment, tumor metabolism and neuro-oncology. We explore the cellular and molecular mechanisms of tumor progression using a wide range of state-of-the-art technologies, including multimodal omics technologies (genomics, metabolomics…), advanced immunoprofiling analyses, as well as ex vivo and in vivo imaging modalities leveraging patient data and innovative patient-derived models for cancer research.
DIRECTOR OF DEPARTMENT
Meiser
- Cancer Metabolism Group
- Cytoskeleton and Cancer Progression
- DNA Repair and Chemoresistance
- In Vivo Imaging
- Luxembourg Centre of Neuropathology
- Multiomics Data Science
- NORLUX Neuro-Oncology Laboratory
- Neuro-Immunology Group
- Translational Radiomics
- Tumor Immunotherapy and Microenvironment
- Tumor Stroma Interactions
VISIT OUR
RESEARCH PORTAL
The LIH Research Portal allows you to search and find information about all active researchers, units, outputs, projects and infrastructures.
Projects & clinical trials
Featured team members
-
Elisabetta
Bartolini PhD Student -
Titiksha
Basu Postdoctoral Fellow -
Alice
Benoit PhD Student -
Amandine
Bernard Laboratory Technician -
Coralie
Borne Postdoctoral Fellow -
Selma
Boudissa Research Engineer -
Eleonora
Campus PhD Student -
Maryna
Chepeleva PhD Student
Scientific publications
-
Actin remodeling in autophagy-mediated tumor immune escape, mechanistic aspects – 08/12/2023
-
CSPG4 CAR-redirected Cytokine Induced Killer lymphocytes (CIK) as effective cellular immunotherapy for HLA class I defective melanoma – 22/11/2023
-
Actin cytoskeleton remodeling at the cancer cell side of the immunological synapse – 21/09/2023
-
The Immunological Synapse Part B – 11/07/2023
-
Correlative light and electron microscopy to explore the lytic immunological synapse between natural killer cells and cancer cells – 05/06/2023
-
Actin cytoskeleton depolymerization increases matrix metalloproteinase gene expression in breast cancer cells by promoting translocation of cysteine-rich protein 2 to the nucleus – 15/05/2023
-
Measuring CTL Lytic Granule Secretion and Target Cell Membrane Repair by Fluorescent Lipophilic Dye Uptake at the Lytic Synapse – 28/04/2023
-
An integrated workflow for phosphopeptide identification in natural killer cells (NK-92MI) and their targets (MDA-MB-231) during immunological synapse formation – 09/02/2023
-
The Immunological Synapse Part A – 11/01/2023
-
Ultrarapid lytic granule release from CTLs activates Ca2+-dependent synaptic resistance pathways in melanoma cells – 01/02/2022
Related News
Forthcoming events
CANBIO
CANBIO is a doctoral research and training unit (DTU) addressing the clinical problem of tumour progression and recurrence. PhD candidates within CANBIO are engaged in a collaborative and interdisciplinary endeavour to deliver novel insight into tumour escape mechanisms, disease monitoring and large scale data analysis in highly malignant cancers.
i2TRON
TTM is taking a leading role in the coordination of i2TRON, a doctoral training unit (DTU) with a strong focus on developing the new generation of translational scientists, who can turn observations in the laboratory, clinical setting or community into interventions that improve the health of individuals via innovative diagnostics or treatments.
Visit the dedicated webpage for more information:
Job vacancies
-
Internship Position in Leukemia Research (Master students) – AL0124 (JF/INT0124/AL/TSI)
Department of Cancer Research – Tumor Stroma Interactions
-
Post-Doctoral Fellow in Cancer Research (MC/PDCR1123/EM/TSI)
Department of Cancer Research – Tumor Stroma Interactions
-
Senior Post-Doctoral Fellow in Immuno-oncology Research (MC/SPDR0723/BJ/TIME)
Department of Cancer Research – Tumor Microenvironment